Question

How are the transgenic mice used in cancer research?

Answer 1

Transgenic mice:

1. Transgenic mice that have been modified using a particular oncogene (cancer-causing gene) and thus developed a certain type of cancer, are useful to answer questions concerning the relationship between oncogenes and cancer development.
2. Theoretically, such animals can also be used for research into cancer treatment and prevention of malignancy.
3. In the laboratory, one such transgenic mouse model for the investigation of breast cancer was developed. The oncogenes Myc and ras were analyzed to find out if they lead to breast cancer in mice transformed with these genes.