Question

How is peptide linkage formed?

Answer 1

1. α-Amino acids are bifunctional compounds containing a carboxylic acid group and an amino group on α-carbon.

2. The reaction of the COOH group of one amino acid molecule and NH2 group of the neighbouring amino acid molecule forms peptide having -CO-NH-linkage by elimination of water.

3. Above reaction repeats itself to give tri, tetra, penta and finally polypeptides

(i.e.,protein).