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प्रश्न
The diagram below shows the sequence of amino acids in part of a haemoglobin molecule.
Key: | Val = valine His = histidine Leu = leucine |
Thr = threonine Pro: proline Glu = glutamic acid |
- If the base T* was substituted with A, how would it affect the haemoglobin chain?
- Name the condition and the effects associated with the above substitution.
उत्तर
- CTT would become CAT which codes for valine. Thus, valine would replace glutamic acid at that point.
- In sickle cell anaemia, the mutant haemoglobin molecule undergoes polymerization leading to the change in the shape of the RBC from a biconcave disc to an elongated sickle-like structure.
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संबंधित प्रश्न
Out of the four phenotypes obtained in F2 generation of dihybrid cross between yellow round and green wrinkled seeds of pea plant, ______.
______ types of gametes will be formed by a pea plant with genotype TtYy.
Identify the characteristics that represent 'Inheritance of blood groups in humans.
- Dominance
- Co-dominance
- Multiple allele
- Incomplete dominance
- Polygenic inheritance
In an experiment on Pisum sativum, Mendel crossed a pure white flowered pea plant with pure purple flowered plant. The first generation of hybrids from the cross should show ____________.
Which of the following is CORRECT with respect to alleles or allelomorphs?
How many types of gametes would be formed by a pure line?
In monohybrid cross between pure tall and pure dwarf pea plant, how many types of genotypes are found in F2 generation?
Identify the genotypic ratio obtained in a Mendelian dihybrid cross.
Mendel may not be able to establish the law of independent assortment, if both characters were located on ____________.
In a cross between a male and female, both heterozygous for sickle cell anaemia gene, what percentage of the progeny will be diseased?