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प्रश्न
What is the difference between agonists and antagonists?
उत्तर
Agonists | Drugs that mimic the natural |
Drugs that mimic the natural | Drugs that bind to the receptor site and |
messenger by switching on the inhibit its natura receptor. | inhibit its natural function are called Antagonists. |
Useful when there is lack of natural chemical messenger. | Useful when blocking of messege in required |
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The most useful classification of drugs for medicinal chemists is ______.
Where are receptors located?
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Match the class of compounds given in Column I with their functions given in Column II.
Column I | Column II |
(i) Antagonists | (a) Communicate message between two neurons and that between neurons to muscles |
(ii) Agonists | (b) Bind to the receptor site and inhibit its natural function |
(iii) Chemical messenger | (c) Crucial to body’s communication process |
(iv) Inhibitors | (d) Mimic the natural messenger |
(v) Receptors | (e) Inhibit activities of enzymes |
Assertion: Receptors are crucial to body’s communication process.
Reason: Receptors are proteins.
Assertion: Chemical messengers are chemicals that enable communication of message between two neurons or between neurons and muscles.
Reason: Chemicals enter the cell through receptor.
Assertion: Chemical messenger gives message to the cell without entering the cell.
Reason: Chemical messenger is received at the binding site of receptor proteins.
Assertion: Receptor proteins show selectivity for one chemical messenger over the other.
Reason: Chemical messenger binds to the receptor site and inhibits its natural function.