Advertisements
Advertisements
Question
Describe Klinefelter’s syndrome.
Solution
- It is a chromosomal disorder caused by an extra X chromosome in males. Thus genotype of individuals is 44 + XXY. They are described as feminized males.
- The extra chromosome is a result of the non-disjunction of the X-chromosome during meiosis in the formation of the ovum.
- Such an individual is male and has overall masculine development. The voice pitch is harsh and has underdeveloped testis. They are tall with long arms, showing feminine development. Voice pitch is harsh and have under developed testis.
- They are tall with long arms, showing feminine development and no spermatogenesis; therefore, individuals are sterile.
APPEARS IN
RELATED QUESTIONS
If only one 'X' chromosome is found in a female person, which of the following symptoms she will show?
- epicanthal skin fold
- webbing of neck
- small testis and absence of spermatogenesis
- presence of simian crease on the palm
Why are color-blindness and thalassaemia categorised as Mendelian disorders? Write the symptoms of these diseases seen in people suffering from them.
Answer the following question.
Both Haemophilia and Thalessemia are blood-related disorders in humans. Write their causes and the difference between the two. Name the category of genetic disorder they both come under.
In human beings 45 chromosomes/single X/XO abnormality causes ______.
Give a detail account of thalassemia.
In sickle-cell anaemia, shape of RBCs under oxygen tension becomes ______.
Extra chromosome ‘X’ is present in which one of the following cases?
If both parents are carriers for thalassaemia, which is an autosomal recessive disorder, what are the chances of pregnancy resulting in an affected child?
The technique exployed in human genetic counselling is:
Select the correct match.