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Question
Describe the structure of Graafian follicle.
Solution
Structure of Graafian follicle:
- The Graafian follicle is a mature ovarian follicle.
- The secondary oocyte is located eccentrically (away from the centre) and is surrounded by a non-cellular layer of zona pellucida secreted by the vitelline membrane of the oocyte,
- There are three layers covering the Graafian follicle. They are as follows:
- The outermost protective and fibrous covering is called theca externa.
- Inner to it is cellular theca interna which produces the hormone estrogen.
- Inner to the theca interna, the follicular cells from the membrane granulosa.
- From the membrane granulosa, the cells differentiate into discus proligerus and the corona radiata cells.
- Oocyte and the surrounding granulosa cells are together termed as Cumulus oophorus.
- A fluid-filled cavity called antrum lies between the oocyte and the membrane granulosa. It is filled with a fluid called liquor folliculi.
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