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Question
Distinguish between Intrinsic and extrinsic process of clotting
Distinguish Between
Solution
| Intrinsic pathway | Extrinsic pathway |
| 1. It is stimulated by damage to blood vessels. | 1. It is stimulated by damage to tissue outside the vessel. |
| 2. It is more complex and takes more time than the extrinsic pathway. | 2. It occurs rapidly as it has fewer steps as compared to the intrinsic pathway. |
| 3. Tissue factor is not involved in the activation of the intrinsic pathway. | 3. Tissue factor also known as thromboplastin activates extrinsic pathways. |
| 4. It involves factor VIII, IX, XI, and XII. | 4. It involves factors VII, X, and V. |
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