Question

During an allergic reaction, the binding of antigen to IgE antibodies initiates release of ______.

Options

• Interferon

• Histamine

• Heparin

• Acetylamine

Answer 1

During an allergic reaction, the binding of antigen to IgE antibodies initiates release of histamine.

Explanation:

During an allergic reaction, antigens bind to IgE antibodies on mast cell or basophil surfaces, causing histamine to be released. Histamine is a substance that causes allergic symptoms such as itching, swelling, and increased blood vessel permeability.