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Question
Explain the importance of epithelial surface in innate immunity.
Solution
Epithelial surface:
The intact skin and mucous membranes (secrete mucous) covering the body, protects against invasion by microorganism(s).
- The healthy skin possesses bactericidal activity due to the presence of high concentrations of salt in drying sweat.
- Sebaceous secretions and long chain of fatty acids have bactericidal and fungicidal properties.
- The mucosa of the respiratory tract has several innate mechanisms of defense.
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