Question

In prokaryotes, the primers of lagging strands are removed by ______.

Options

• 3' -5' exonucleous

• DNA ligase

• DNA polymerase-I

• DNA polymerase-III

Answer 1

In prokaryotes, the primers of lagging strands are removed by  DNA polymerase-I.

Explanation:

Depending on whether this is happening on the leading or lagging strand (Okazaki fragment) of the DNA, DNA polymerase III will next synthesise a continuous or discontinuous strand of DNA. Due of its high processivity, DNA polymerase III can synthesise DNA very quickly. The fact that the -clamps "hold" on to the DNA strands is part of what causes this high processivity.