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Question
Select the correct statement from the following.
Options
UAA, UAG, and UGA code for the same amino acid.
Frameshift mutations are caused due to insertion or deletion of three or multiple three nitrogen bases.
Sickle-cell anemia is caused as a result of point mutation.
Codon on mRNA is represented in 3' AUG 5' while anticodon on tRNA is represented as 5' UAC 3'.
Solution
Sickle-cell anemia is caused as a result of point mutation.
Explanation:
The correct answer is that Sickle-cell anaemia is caused by a point mutation.
Sickle-cell anaemia is caused by a single base pair point mutation that results in the substitution of valine for glutamic acid.
Statements a, b, and d are wrong and should be corrected as follows:
(a) The stop codons UAA, UAG, and UGA do not code for amino acids.
(b) Frameshift mutations result from the insertion and deletion of nucleotide bases in non-multiples of three.
(d) The mRNA codon is represented by 5' AUG 3', while the tRNA anticodon is represented by 3' UAC 5'.
