Question

Thalassemia and sickle cell anaemia are caused due to a problem in globin molecule synthesis. Identify the correct statement from the following.

Options

• Sickle cell anaemia is due to a quantitative problem of globin molecules.

• Both are due to a quantitative defect in globin chain synthesis.

• Thalassemia is due to less synthesis of globin molecules.

• Both are due to a qualitative defect in globin chain synthesis.

Answer 1

Thalassemia is due to less synthesis of globin molecules.

Explanation:

Thalassemia is a quantitative problem of synthesizing fewer globin chains whereas sickle cell anaemia is a qualitative problem in which the body produces fewer globin chains.

The molecule of mutant hemoglobin is formed.