Question

The oxygen dissociation curve is a sigmoid curve and it shifts towards the right due to ______.

Options

• decrease in H⁺ concentration

• increase in pCO₂ in blood.

• decrease in pO₂

• decrease in 2, 3 diphosphoglycerate (DPG) in RBCs

Answer 1

The oxygen dissociation curve is a sigmoid curve and it shifts towards the right due to an increase in pCO₂ in blood.

Explanation:

The oxygen dissociation curve, also known as the oxygen haemoglobin dissociation curve, is a curve that illustrates or correlates haemoglobin oxygen saturation over a range of oxygen pressures.

The right shift in the curve is caused by an increase in blood CO₂ partial pressure (pCO₂). As a result, haemoglobin has a lower affinity for oxygen.