Question

Transplantation of tissues/organs to save certain patients often fails due to rejection of such tissues/organs by the patient. Which type of immune response is responsible for such rejections?

Options

• Auto-immune response

• Humoral immune response

• Physiological immune response

• Cell-mediated immune response

Answer 1

Cell-mediated immune response

Explanation:

Graft rejection is caused by the cell-mediated immune response. Tissue and blood group matching are required prior to any graft/transplant, and the patient must continue to take immunosuppressants for the rest of his or her life because the body can distinguish between "self" and "non-self."