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Why does a patient of ADA - deficiency require repeated infusions of genetically engineered lymphocytes? - Biology

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Question

Why does a patient of ADA - deficiency require repeated infusions of genetically engineered lymphocytes?

Short Answer

Solution

Infusions of genetically modified lymphocytes that express the ADA enzyme help briefly restore immune function in people who don't have enough of it. But because these cells don't live forever, the patient needs to be given injections of genetically modified lymphocytes on a regular basis.

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