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Question
Write short notes on Myosin filament.
Short Note
Solution
Myosin filament:
- Each myosin filament is a polymerized protein. Many meromyosins (monomeric proteins) constitute one thick filament.
- Myosin molecule consists of two heavy chains (heavy meromyosin / HMM) coiled around each other forming a double helix. One end of each of these chains is projected outwardly is known as a cross bridge. This end folds to form a globular protein mass called myosin head.
- Two light chains are associated with each head forming 4 light chains/light meromyosin/LMM.
- Myosin head has a special ATPase activity. It can split ATP to produce energy.
- Myosin contributes 55% of muscle proteins.
- In sarcomere, myosin tails are arranged to point towards the centre of the sarcomere and the heads point to the sides of the myofilament band.
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