Question

Amongst the given set of reactants, the most appropriate for preparing 2° amine is ______.

विकल्प

• $$2°\mathrm{R}-\mathrm{Br}+\mathrm{NH}{\phantom{A}}_3$$

• $$2°\mathrm{R}-\mathrm{Br}+\mathrm{NaCN}\mathrm{followed}\mathrm{by}\mathrm{H}{\phantom{A}}_2/\mathrm{Pt}$$

• $$1°\mathrm{R}-\mathrm{NH}{\phantom{A}}_2+\mathrm{RCHO}\mathrm{followed}\mathrm{by}\mathrm{H}{\phantom{A}}_2/\mathrm{Pt}$$

• $$1°\mathrm{R}-\mathrm{Br}(2\mathrm{mol})+\mathrm{potassium}\mathrm{phthalimide}\mathrm{followed}\mathrm{by}\mathrm{H}{\phantom{A}}_3\mathrm{O}{\phantom{A}}^{+}/\mathrm{heat}$$

Answer 1

Amongst the given set of reactants, the most appropriate for preparing 2° amine is $$1°\mathrm{R}-\mathrm{NH}{\phantom{A}}_2+\mathrm{RCHO}\mathrm{followed}\mathrm{by}\mathrm{H}{\phantom{A}}_2/\mathrm{Pt}$$.

Explanation:

$$\underset{1°\mathrm{Amine}}{\mathrm{R}-\mathrm{NH}{\phantom{A}}_2}+\underset{\mathrm{Aldehyde}}{\mathrm{O}=\mathrm{HCR}}\underset{\mathrm{amination}}{\overset{\mathrm{Reductive}}{\to }}\mathrm{R}-\mathrm{N}-\mathrm{CHR}\underset{\mathrm{Reduction}}{\overset{\mathrm{H}{\phantom{A}}_2/\mathrm{Pt}}{\to }}\underset{2°\mathrm{Amine}}{\mathrm{RNH}-\mathrm{CH}{\phantom{A}}_2\mathrm{R}}$$