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प्रश्न
For an organ transplant, it is an advantage to have an identical twin. Why?
उत्तर
Very often, when some human organs like heart, eye, liver, and kidney fail to function satisfactorily, transplantation is the only remedy to enable the patient to live a normal life. Then a search begins to find a suitable donor.
Grafts from just any source-an animal, another primate, or any human beings cannot be made since the grafts would be rejected sooner or later. Tissue matching, blood group matching are essential before undertaking any graft/transplant and even after this the patient has to take immuno-suppresants all his/her life. The body is able to differentiate ‘self ’ and ‘nonself’ and the cell-mediated immune response is responsible for the graft rejection. In an identical twin, there is no chance of rejection of the transplanted organ, so it is advantageous.
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संबंधित प्रश्न
What are the cells involved innate immune system?
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Why is an antibody molecule represented as H2L2?
| Robert was suffering from chronic renal failure. At the doctors’ recommendation of transplantation of kidney received from a healthy donor, Robert underwent kidney transplant. However, after two weeks, the transplanted kidney was rejected by the immune system of Robert. |
- Identify and define the type of immune response that is responsible for the rejection of the grafted organ.
- Suggest a clinical method by which the rejection of the transplanted organ can be prevented.
