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Questions
Answer the following question.
Discuss “The respiratory pathway is an amphibolic pathway”.
Answer the following question.
Why is Krebs cycle reffered as amphibolic pathway?
Solution
- Respiration is considered as a catabolic process; however, it is not entirely correct in case of Krebs cycle.
- Many reactions of Krebs cycle involve oxidation of acetyl CoA to release energy and CO2.
- However, the breakdown of respiratory substrates provides intermediates like α-ketoglutarate, oxaloacetate is used as precursors for the synthesis of fatty acids, glutamic acid and aspartic acid respectively.
- Thus, as the same respiratory process acts as catabolic as well as an anabolic pathway for synthesis of various intermediate metabolic products, it is called an amphibolic pathway.
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