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Question
Differentiate between Somatic cell gene therapy and germline gene therapy.
Distinguish Between
Solution
| Somatic Cell Gene Therapy | Germ Line Gene Therapy |
| 1. Therapeutic genes transferred into the somatic cells. | 1. Therapeutic genes transferred into the germ cells. |
| 2. Introduction of genes into bone marrow cells, blood cells, skin cells, etc. | 2. Genes introduced into eggs and sperms. |
| 3. It Will not be inherited in later generations. | 3. It Will not be inherited in later generations. |
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Gene Therapy
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RELATED QUESTIONS
Gene therapy is an attempt to correct a Genetic defect by providing a normal gene into the individual. By this the function can be restored. An alternate method would be to provide gene product known as enzyme replacement therapy, which would also restore the function. Which in your opinion is a better option? Give reasons for your answer.
One of the applications of biotechnology is ‘gene therapy” to treat a person born with a hereditary disease.
i) What does “gene therapy” mean?
ii) Name the hereditary disease for which the first clinical gene therapy was used.
iii) Mention the steps involved in gene therapy to treat this disease.
