Question

Gene therapy is an attempt to correct a Genetic defect by providing a normal gene into the individual. By this the function can be restored. An alternate method would be to provide gene product known as enzyme replacement therapy, which would also restore the function. Which in your opinion is a better option? Give reasons for your answer.

Answer 1

Though both Gene therapy and Enzyme replacement therapy helps to restore genetic defects, Gene therapy is much better than Enzyme replacement therapy. Because, in Gene therapy, once the defective gene is repaired using a normal gene, the affected individual gains complete recovery whereas, in Enzyme replacement therapy, the respective enzyme or protein has to be provided periodically and does not offer a permanent cure. Moreover, when compared to Gene therapy, Enzyme replacement therapy is highly expensive.