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Question
How does initiation of the translation process occur in prokaryotes? Explain.
Solution
For initiation, the ribosome binds to the mRNA at the start codon (AUG) that is recognised only by the initiator tRNA. The ribosome proceeds to the elongation phase of protein synthesis. During this stage, complexes composed of an amino acid linked to tRNA, sequentially bind to the appropriate codon in mRNA by forming complementary base pairs with the tRNA anticodon. The ribosome moves from codon to codon along the mRNA. Amino acids are added one by one, translated into Polypeptide sequences dictated by DNA and represented by mRNA. At the end, a release factor binds to the stop codon, terminating translation and releasing the complete polypeptide from the ribosome.
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RELATED QUESTIONS
Briefly describe the following:
Translation
An operon is a: ______
The process of translation is ______.
The three codons which result in the termination of polypeptide chain synthesis are ______.
UTRs are the untranslated regions present on ______.
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Which of the following are correct statements for a tRNA molecule?
- It is an adapter molecule.
- Previously called sRNA (soluble RNA)
- tRNA has a codon loop that has bases complementary to the code,
- it also has an amino acid accepter end to which it binds to amino acids.
- It is non-specific for each amino acid.
The first phase of translation is ______
Aminoacylation of tRNA also known as ______.
The process of translation is ______.