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Question
Why do doctors have to carry many tests for selecting a person to be a suitable donor for someone who is going for an organ transplant and not take the organ from just any body? Explain giving reason.
Solution
Because it is grafted and would be rejected sooner or later. Tissue matching and blood group matching are essential before undertaking any graft/transplant and even after this, the patient has to take immune suppressants all his/her life. The body is able to differentiate ‘self’ and ‘nonself’ and the cell-mediated immune response is responsible for graft rejection.
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| Robert was suffering from chronic renal failure. At the doctors’ recommendation of transplantation of kidney received from a healthy donor, Robert underwent kidney transplant. However, after two weeks, the transplanted kidney was rejected by the immune system of Robert. |
- Identify and define the type of immune response that is responsible for the rejection of the grafted organ.
- Suggest a clinical method by which the rejection of the transplanted organ can be prevented.
