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Question
Write the structures of fragments produced on complete hydrolysis of DNA. How are they linked in DNA molecule? Draw a diagram to show pairing of nucleotide bases in double helix of DNA.
Solution
Complete hydrolysis of DNA (or RNA) yields a pentose sugar, phosphoric acid and nitrogen-containing heterocyclic compounds (called bases). In DNA molecules, the sugar moiety is β-D-2-deoxyribose whereas in RNA molecule, it is β-D-ribose.
Two nucleic acid chains are wound about each other and held together by hydrogen bonds between pairs of bases. The two strands are complementary to each other because the hydrogen bonds are formed between specific pairs of bases.
Double strand helix structure for DNA
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