Question

Acetamide is amphoteric in nature. Give two equations to support this statement.

Answer 1

Basic nature of acetamide: It reacts with acids and form salts. e.g;
$$\mathrm{CH}{\phantom{A}}_3\mathrm{CONH}{\phantom{A}}_2+\mathrm{HCl}⟶\underset{\text{Acetamide hydrochloride}}{\mathrm{CH}{\phantom{A}}_3\mathrm{CON}{\phantom{A}}^{+}\mathrm{H}{\phantom{A}}_3\mathrm{Cl}{\phantom{A}}^{-}}$$

Acidic nature of acetamide: It liberates hydrogen gas when treated with reactive metals.
$$2\mathrm{CH}{\phantom{A}}_3\mathrm{CONH}{\phantom{A}}_2+2\mathrm{Na}⟶2\mathrm{CH}{\phantom{A}}_3\mathrm{CONHNa}+\mathrm{H}{\phantom{A}}_2\uparrow$$