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प्रश्न
What is DNA polymorphism? Why is it important to study it?
उत्तर
Polymorphism (variation at genetic level) arises due to mutations. Allelic sequence variation has traditionally been described as a DNA polymorphism if more than one variant (allele) at a locus occurs in human population with a frequency greater than 0.01. In simple terms, if an inheritable mutation is observed in a population at high frequency, it is referred to as DNA polymorphism. Polymorphism become very useful identification tool in forensic applications. Further, as the polymorphisms are inheritable from parents to children, DNA fingerprinting is the basis of paternity testing, in case of disputes.
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संबंधित प्रश्न
Following the collision of two trains a large number of passengers are killed. A majority of them are beyond recognition. Authorities want to hand over the dead to their relatives. Name a modern scientific method and write the procedure that would help in the identification of kinship.
For DNA fingerprinting radioactive probe obtained from __________ is used in India.
(A) Banded Krait
(B) King Cobra
(C) Viper
(D) Rat snake
Name the radioactive probe used in India for DNA fingerprinting.
Mention how does DNA polymorphism arise in a population.
What is the use of southern blotting in DNA fingerprinting?
What are the different types of mutations?
ln which of the following technique DNA bands are transferred from agarose gel to nitrocellulose or nylon membrane?
DNA having variable length obtained by restriction digestion is called ______.
ln DNA profiling technique, the nitrocellulose paper is used in the process called ____________.
Which of the following is not true with respect to INA fingerprinting?
- DNA fingerprinting technique was first developed by Alec Jeffrey.
- DNA profiling is a more recent and more sensitive version of DNA fingerprinting.
- DNA fingerprinting was first used in Britain to verify the parentage of an immigrant, who had left the country and then wanted to return
- In DNA fingerprinting, single stranded radioactive DNA is used as probes.
Choose the correct option.
