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Question
What is DNA polymorphism? Why is it important to study it?
Solution
Polymorphism (variation at genetic level) arises due to mutations. Allelic sequence variation has traditionally been described as a DNA polymorphism if more than one variant (allele) at a locus occurs in human population with a frequency greater than 0.01. In simple terms, if an inheritable mutation is observed in a population at high frequency, it is referred to as DNA polymorphism. Polymorphism become very useful identification tool in forensic applications. Further, as the polymorphisms are inheritable from parents to children, DNA fingerprinting is the basis of paternity testing, in case of disputes.
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RELATED QUESTIONS
The genetic marker used as key factor in DNA fingerprinting is _______.
(A) VNTRs
(B) Exons
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(D) DNA probes
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Repetitive DNA and Satellite DNA
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____________ are the DNA sequences which are useful in DNA fingerprinting.
____________ paper is used for embedding DNA strands in Southern blotting technique.
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- Gel electrophoresis
- Isolation of DNA
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- Restriction digestion
