Advertisements
Advertisements
प्रश्न
Explain how recombinant human insulin was prepared in 1983 by Eli Lily an American company.
उत्तर
1983, Eli Lilly an American company prepared two DNA sequences corresponding to A and B, chains of human insulin and introduced them in plasmids of E. coli to produce insulin chains. Chains A and B were produced separately, extracted and combined by creating disulfide bonds to form human insulin.
APPEARS IN
संबंधित प्रश्न
How did an American Company, Eli Lilly use the knowledge of r-DNA technology to produce human insulin?
Explain how insulin can be produced using recombinant DNA technology.
Answer the following question.
Explain the various steps involved in the production of artificial insulin.
How many amino acids are arranged in the two chains of Insulin?
Choose the correct option regarding retrovirus.
When gene targetting involving gene amplification is attempted in an individual’s tissue to treat disease, it is known as ______
With regard to insulin choose the correct options.
- C-peptide is not present in mature insulin.
- The insulin produced by rDNA technology has C-peptide.
- The pro-insulin has C-peptide.
- A-peptide and B-peptide of insulin are interconnected by disulphide bridges.
Choose the correct answer from the options given below.
Define Antigen and Antibody. Name any two diagnostic kits based upon them.
A patient is suffering from ADA deficiency. Can he be cured? How?
A host cell must be made competent, before it is able to receive an rDNA. Justify.
