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प्रश्न
A host cell must be made competent, before it is able to receive an rDNA. Justify.
उत्तर
Because DNA molecules are hydrophilic, they cannot cross cell membranes. Recombinant DNA must be injected into the cell in order for it to be integrated into the vector or host genome. Making the host cells capable of receiving the rDNA is crucial.
संबंधित प्रश्न
Explain enzyme – replacement therapy to treat adenosine deaminase deficiency. Mention two disadvantages of this procedure.
Recombination DNA−technology is of great importance in the field of medicine. With the help of a flow chart, show how this technology has been used in preparing genetically engineered human insulins.
What is gene therapy? Illustrate using the example of adenosine deaminase (ADA) deficiency.
Consult internet and find out how to make orally active protein pharmaceutical. What is the major problem to be encountered?
State the cause of ADA deficiency in humans.Mention a possible cure for an ADA deficiency patient.
Expand the Given and mention one application of each:
ELISA
How was Insulin obtained before the advent of rDNA technology? What were the problems encountered?
Explain how ADA deficiency can be corrected?
What are DNA vaccines?
Can a disease be detected before its symptoms appear? Explain the principle involved.
