Advertisements
Advertisements
प्रश्न
What are DNA vaccines?
उत्तर
Genetic immunization by using DNA vaccines is a novel approach that came into being in 1990. The immune response of the body is stimulated by a DNA molecule. A DNA vaccine consists of a gene encoding an antigenic protein, inserted onto a plasmid, and then incorporated into the cells in a target animal. DNA instructs the cells to make antigenic molecules which are displayed on its surfaces. This would evoke an antibody response to the free-floating antigen secreted by the cells. The DNA vaccine cannot cause the disease as it contains only copies of a few of its genes. DNA vaccines are relatively easy and inexpensive to design and produce.
संबंधित प्रश्न
Why do children cured by enzyme-replacement therapy adenosine deaminase deficiency need periodic treatment?
Expand the Given and mention one application of each:
PCR
Diagrammatically represent the experimental steps in cloning and expressing an human gene (say the gene for growth hormone) into a bacterium like E. coli?
Explain how insulin can be produced using recombinant DNA technology.
Describe the role of bacterium Thermus aquaticus in carrying the process of polymerase chain reaction.
The first clinical gene therapy was done for the treatment of ________.
Mention the number of primers required in each cycle of PCR. Write the role of primers and DNA polymerase in PCR. Name the source organism of the DNA polymerase used in PCR.
Explain how “Rosie” is different from a normal cow.
PCR is a useful tool for early diagnosis of an Infectious disease. Elaborate.
Explain how recombinant Insulin can be produced.
C-peptide of human insulin is ______.
A probe which is a molecule used to locale-specific sequences in a mixture of DNA or RNA Mole cubs could be ______.
Choose the correct option regarding retrovirus.
Give the full form of ELISA. Which disease can be detected using it? Discuss the principle underlying the test.
How is a mature, functional insulin hormone different from its prohormone form?
A host cell must be made competent, before it is able to receive an rDNA. Justify.
In humans, somatic gene therapy was carried out to correct an immunodeficiency disease. Name this disease.
Give a reason for the following:
Streptokinase is administered to the patients having myocardial infarction.
How many cycles of PCR are required to produce 250 molecules of DNA, starting with a single parental strand?