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Question
Assertion: Enzymes have active sites that hold substrate molecule for a chemical reaction.
Reason: Drugs compete with natural substrate by attaching covalently to the active site of enzyme.
Options
Assertion and reason both are correct statement but reason does not explain assertion.
Assertion and reason both are correct and reason explains the assertion.
Both assertion and reason are wrong statement.
Assertion is correct statement reason is wrong statement.
Assertion is wrong statement reason is correct statement.
Solution
Assertion is correct statement reason is wrong statement.
Explanation:
Drugs compete with natural substrate by attaching by weak bonds such as ionic bonding. H-bonding, van der Waals interaction, etc., to the active site of the enzyme.
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RELATED QUESTIONS
Which forces are involved in holding the drugs to the active site of enzymes?
Which of the following statements is correct?
Which of the following is not a target molecule for drug function in body?
Which of the following statements is not true about enzyme inhibitors?
Which site of an enzyme is called allosteric site?
What type of forces are involved in binding of substrate to the active site of enzyme?
Explain the role of allosteric site in enzyme inhibition?
What happens when the bond formed between an enzyme and an inhibitor is a strong covalent bond?
Assertion: Competitive inhibitors compete with natural substrate for their attachment on the active sites of enzymes.
Reason: In competitive inhibition, inhibitor binds to the allosteric site of the enzyme.
What are enzyme inhibitors? Classify them on the basis of their mode of attachments on the active site of enzymes. With the help of diagrams explain how do inhibitors inhibit the enzymatic activity.
