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प्रश्न
Assertion: Enzymes have active sites that hold substrate molecule for a chemical reaction.
Reason: Drugs compete with natural substrate by attaching covalently to the active site of enzyme.
पर्याय
Assertion and reason both are correct statement but reason does not explain assertion.
Assertion and reason both are correct and reason explains the assertion.
Both assertion and reason are wrong statement.
Assertion is correct statement reason is wrong statement.
Assertion is wrong statement reason is correct statement.
उत्तर
Assertion is correct statement reason is wrong statement.
Explanation:
Drugs compete with natural substrate by attaching by weak bonds such as ionic bonding. H-bonding, van der Waals interaction, etc., to the active site of the enzyme.
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संबंधित प्रश्न
Name the macromolecules that are chosen as drug targets.
Which of the following statements is correct?
Which of the following is not a target molecule for drug function in body?
Which of the following statements is not true about enzyme inhibitors?
What type of forces are involved in binding of substrate to the active site of enzyme?
Why are certain drugs called enzyme inhibitors?
What happens when the bond formed between an enzyme and an inhibitor is a strong covalent bond?
Assertion: Competitive inhibitors compete with natural substrate for their attachment on the active sites of enzymes.
Reason: In competitive inhibition, inhibitor binds to the allosteric site of the enzyme.
Assertion: Non-competitive inhibitor inhibits the catalyic activity of enzyme by binding with its active site.
Reason: Non-competitive inhibitor changes the shape of the active site in such a way that substrate can’t recognise it.
How do enzymes catalyse a chemical reaction in the living system? Explain drug target interaction taking the example of enzyme as target.
