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प्रश्न
Why are certain drugs called enzyme inhibitors?
उत्तर
Enzymes have active sites that bind the substrate for effective and quick chemical reaction. The functional groups present at the active site of enzyme interact with functional groups of substrate via ionic bonding, hydrogen bonding, van der Waal interaction etc. Some drugs interfere with this interaction by blocking the binding site of enzyme and prevent the binding of actual substrate with enzyme. This inhibits the catalytic activity of the enzyme, therefore, these are called inhibitors.
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संबंधित प्रश्न
Name the macromolecules that are chosen as drug targets.
Which of the following statements is correct?
Which of the following statements is not true about enzyme inhibitors?
Which site of an enzyme is called allosteric site?
What type of forces are involved in binding of substrate to the active site of enzyme?
Explain the role of allosteric site in enzyme inhibition?
What happens when the bond formed between an enzyme and an inhibitor is a strong covalent bond?
Assertion: Enzymes have active sites that hold substrate molecule for a chemical reaction.
Reason: Drugs compete with natural substrate by attaching covalently to the active site of enzyme.
Assertion: Non-competitive inhibitor inhibits the catalyic activity of enzyme by binding with its active site.
Reason: Non-competitive inhibitor changes the shape of the active site in such a way that substrate can’t recognise it.
How do enzymes catalyse a chemical reaction in the living system? Explain drug target interaction taking the example of enzyme as target.
