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प्रश्न
Why are certain drugs called enzyme inhibitors?
उत्तर
Enzymes have active sites that bind the substrate for effective and quick chemical reaction. The functional groups present at the active site of enzyme interact with functional groups of substrate via ionic bonding, hydrogen bonding, van der Waal interaction etc. Some drugs interfere with this interaction by blocking the binding site of enzyme and prevent the binding of actual substrate with enzyme. This inhibits the catalytic activity of the enzyme, therefore, these are called inhibitors.
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संबंधित प्रश्न
Name the macromolecules that are chosen as drug targets.
Which forces are involved in holding the drugs to the active site of enzymes?
Which of the following statements is correct?
Which site of an enzyme is called allosteric site?
What type of forces are involved in binding of substrate to the active site of enzyme?
Explain the role of allosteric site in enzyme inhibition?
What happens when the bond formed between an enzyme and an inhibitor is a strong covalent bond?
Assertion: Enzymes have active sites that hold substrate molecule for a chemical reaction.
Reason: Drugs compete with natural substrate by attaching covalently to the active site of enzyme.
Assertion: Non-competitive inhibitor inhibits the catalyic activity of enzyme by binding with its active site.
Reason: Non-competitive inhibitor changes the shape of the active site in such a way that substrate can’t recognise it.
What are enzyme inhibitors? Classify them on the basis of their mode of attachments on the active site of enzymes. With the help of diagrams explain how do inhibitors inhibit the enzymatic activity.
