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Questions
What happens when Anisole is treated with CH3Cl/anhydrous AlCl3?
What happens when Anisole is treated with CH3Cl/anhydrous AlCl3?
Write the chemical equation in support of your answer.
Solution
This reaction is an example of Friedel-Crafts alkylation. The alkyl groups (methyl) are introduced at ortho and para positions by reaction with an alkyl halide (methyl halide) in the presence of anhydrous aluminium chloride (a Lewis acid) as a catalyst forming methoxy toluene.
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