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प्रश्न
What is genetically engineered Insulin?
उत्तर
The insulin synthesized by recombinant DNA technology is called genetically engineered Insulin. It was the first-ever pharmaceutical product of DNA technology. In 1986, human insulin was marked under the trade name Humulin.
संबंधित प्रश्न
Why do children cured by enzyme-replacement therapy adenosine deaminase deficiency need periodic treatment?
Write the function of adenosine deaminase enzyme.
Compare and contrast the advantages of production of genetically modified crops.
What is gene therapy? Illustrate using the example of adenosine deaminase (ADA) deficiency.
State the best-known contribution of P.K. Sethi
Give a schematic representation of the transformation of a pro-insulin into insulin.
The first clinical gene therapy was done for the treatment of ________.
How is the amplification of a gene sample of interest carried out using PCR?
Explain how “Rosie” is different from a normal cow.
How was Insulin obtained before the advent of rDNA technology? What were the problems encountered?
Which of the following is the correct sequence of steps in a PCR (Polymerase Chain Reaction)?
When gene targetting involving gene amplification is attempted in an individual’s tissue to treat disease, it is known as ______
With regard to insulin choose the correct options.
- C-peptide is not present in mature insulin.
- The insulin produced by rDNA technology has C-peptide.
- The pro-insulin has C-peptide.
- A-peptide and B-peptide of insulin are interconnected by disulphide bridges.
Choose the correct answer from the options given below.
Can a disease be detected before its symptoms appear? Explain the principle involved.
Define Antigen and Antibody. Name any two diagnostic kits based upon them.
How is a mature, functional insulin hormone different from its prohormone form?
In humans, somatic gene therapy was carried out to correct an immunodeficiency disease. Name this disease.
The diagram given below represents the schematic structure of proinsulin, which undergoes certain modifications before it becomes a fully functional insulin.
Study the diagram carefully and answer the questions that follow:
- State the change the proinsulin undergoes to become fully functional.
- Name the modern scientific technique used for the production of human insulin.
- How are the two polypeptide chains of the fully functional insulin held together?
