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Question
Write the equations involved in the following reactions : Williamson synthesis
Solution 1
Solution 2
Williamson synthesis: It involves the treatment of an alkyl halide with a suitable sodium alkoxide. The sodium alkoxide needed for the purpose is prepared by the action of sodium on a suitable alcohol. The reaction invlolves the nucleophillic displacement (substitution) of the halide ion from the alkyl halide by the alkoxide ion by SN2 mechanism.
R-OH +2Na → 2R’-O-Na+ + H2
R’-O-Na+ + R-X → R’-O-R +Na+ X
Ether
The second reaction is the substitution nucleophillic bimolecular (SN2) reaction.
For example:
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