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Question
Can Gatterman-Koch reaction be considered similar to Friedel Craft’s acylation? Discuss.
Solution
Gattermann-Koch reaction is formylation (introduction of-CHO group) to the benzene nucleus. Friedel-Crafts acylation reaction is introduction of RCO-group in the benzene ring.
In Friedel-Crafts acylation reactions, the benzene is treated with an acid chloride in presence of anhydrous \[\ce{AlCl3}\]. So, Gattermann-Koch reaction can be considered similar to Friedel-Crafts acylation reaction.
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