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Question
Distinguish between exonuclease and endonuclease
Solution
Sr. No. | Exonuclease | Endonuclease |
1. |
It is a type of restriction enzyme that removes the nucleotide from the 5’ or 3’ ends of the DNA molecule. |
It is a type of restriction enzyme that makes a cut within the DNA at a specific site to generate sticky ends. |
2. |
They separated DNA base pairs at their terminal ends. |
They separate DNA at any location other than the terminal ends. |
3. | They work on single strands of DNA or gaps in double-stranded DNA. | They cut one or both strands of double-stranded DNA. |
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