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Explain formation of peptide linkage in protein with an example. - Chemistry

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Question

Explain formation of peptide linkage in protein with an example.

Short Note

Solution

Proteins are polymers of α-amino acid, and a huge number of α-amino acid peptide bonds connect them (amide bond).

A peptide bond is a chemical link produced between two molecules when one of their carboxyl groups combines with the amino group of the other releasing a water molecule (H2O). This is a dehydration synthesis reaction (also known as a condensation reaction) that happens most commonly between amino acids.

For example:

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2021-2022 (March) Set 1

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\[\ce{\underset{(Glycine)}{H2N - CH2 - COOH}}\]; 

\[\begin{array}{cc}
\ce{H2N - CH2 - COOH}\\
|\phantom{......}\\
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\end{array}\]


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