हिंदी

Answer the following Explain Gabriel phthalimide synthesis. - Chemistry

Advertisements
Advertisements

प्रश्न

Answer the following

Explain Gabriel phthalimide synthesis.

संक्षेप में उत्तर

उत्तर

This method is used for the synthesis of primary amine. It involves the following three stages.

i. Formation of the potassium salt of phthalimide from phthalimide on reaction with alcoholic potassium hydroxide.

ii. Formation of N-alkyl phthalimide from the potassium salt by reaction with an alkyl halide.

iii. Alkaline hydrolysis of N-alkyl phthalimide to form the corresponding primary amine.

shaalaa.com
  क्या इस प्रश्न या उत्तर में कोई त्रुटि है?
अध्याय 13: Amines - Exercises [पृष्ठ २९७]

APPEARS IN

बालभारती Chemistry [English] 12 Standard HSC
अध्याय 13 Amines
Exercises | Q 3.06 | पृष्ठ २९७

संबंधित प्रश्न

How are propan-1-amine and propan-2-amine prepared from oxime?


Write the chemical equation involved in the following reaction:

Hoffmann-bromamide degradation reaction


Give the structures of A, B and C in the following reaction:


Give the structures of A, B and C in the following reaction.


Write the reactions of aromatic with nitrous acid.


Explain the mechanism of action of hydroiodic acid on 3-methylbutan-2-ol.


Identify 'A' and 'B' in the following reaction and rewrite the complete reaction :


Give the structures of A, B and C in the following reactions :


Account for the following:
Gabriel phthalimide synthesis is not preferred for preparing aromatic primary amines.


Answer the following

Explain the ammonolysis of alkyl halides.


Write reactions to prepare ethanamine from Acetonitrile.


The following amines is the product of Gabriel phthalimide synthesis.


Write the order of reactivity of alkyl halides with ammonia.


Write reactions to bring about the following conversions.

Acetamide to methylamine


Identify compound 'B' in following series of reactions?

\[\ce{Acetonitrile ->[Na/alcohol] A ->[NaNO2/dil.HCI] B}\]


\[\ce{CH3-CN ->[Na/C2H5OH]}\]

The product formed is ____________.


Identify 'A' and 'B' in the following conversions.

\[\ce{CH3 - I ->[Alc. KCN][\Delta] A ->[Na/C2H5OH] B}\]


Identify product B in the following reaction.

\[\ce{Aniline ->[NaNO2][HCl] A ->[KI] B}\]


Which of the following reagents is used in Hofmann's elimination reaction of amines?


Which of the following compounds is obtained when quaternary ammonium hydroxide is strongly heated?


Amongst the following, the strongest base in aqueous medium is ______.


Benzylamine may be alkylated as shown in the following equation:

\[\ce{C6H5CH2NH2 + R - X -> C6H5CH2NHR}\]

Which of the following alkylhalides is best suited for this reaction through SN1 mechanism?


Amongst the given set of reactants, the most appropriate for preparing 2° amine is ______.


The best reagent for converting 2–phenylpropanamide into 2-phenylpropanamine is ______.


Among the following amines, the strongest Brönsted base is:


Which of the following methods of preparation of amines will give same number of carbon atoms in the chain of amines as in the reactant?


Reduction of nitrobenzene by which of the following reagent gives aniline?

(i) \[\ce{Sn/HCl}\]

(ii) \[\ce{Fe/HCl}\]

(iii) \[\ce{H2 - Pd}\]

(iv) \[\ce{Sn/NH4OH}\]


What is the product when \[\ce{C6H5CH2NH2}\] reacts with \[\ce{HNO2}\]?


Identify A and B in the following reaction.


How will you carry out the following conversion?


Match the reactions given in Column I with the statements given in Column II.

  Column I   Column II
(i) Ammonolysis (a) Amine with lesser number of carbon atoms
(ii) Gabriel phthalimide synthesis (b) Detection test for primary amines.
(iii) Hoffmann Bromamide reaction (c) Reaction of phthalimide with \[\ce{KOH}\] and \[\ce{R-X}\]
(iv) Carbylamine reaction (d) Reaction of alkylhalides with \[\ce{NH3}\]

Assertion: Only a small amount of \[\ce{HCl}\] is required in the reduction of nitro compounds with iron scrap and \[\ce{HCl}\] in the presence of steam.

Reason: \[\ce{FeCl2}\] formed gets hydrolysed to release \[\ce{HCl}\] during the reaction.


The Gabriels' phthalimide synthesis is used in the synthesis of


A primary amine is formed by an amide on treatment with bromine and alkali. The primary amine has


Ethylamine can be prepared by the action of bromine and caustic potash on which compound?


Reduction of nitro alkanes yields which compound?


Which of the following CANNOT be prepared by ammonolysis of alkyl halide?


Give reasons for the following:

Ammonolysis of alkyl halides is not a good method to prepare pure primary amines.


Which of the following compound gives pink colour on reaction with phthalic anhydride in cone. H2SO4 followed by treatment with NaOH?


Which of the following reaction DOES NOT involve Hoffmann bromamide degradation?


Which of the following amines can be prepared by Gabriel phthalimide reaction?


  1. Phenyl methenamine
  2. N, N - Dimethylaniline
  3. N - Methyl aniline
  4. Benzenamine

Choose the correct order of the basic nature of the above amines.


The amine 'A' when treated with nitrous acid gives yellow oily substance. The amine A is ______.


What is the IUPAC name of \[\ce{(CH3)2 - N - CH3}\]?


Identify the product ‘C’ in the following reaction.

\[\ce{Aniline ->[(CH3CH)2O][Pyridine] A ->[Br2][CH3COOH] B ->[H^+ or OH^-] C}\]


Write the name of the product formed by the action of LiAlH4/ether on acetamide.


Which of the following would not be a good choice for reducing nitrobenzene to aniline?


Write short note on the following:

Ammonolysis


Write a short note on the following:

Ammonolysis


Share
Notifications

Englishहिंदीमराठी


      Forgot password?
Use app×